KPV research: overview and resources
What KPV research material is, how it is characterized, and where to find every specification, method, lot record and reference KPV Labs publishes about it.
What is KPV?
KPV is the tripeptide Lys-Pro-Val. It is the C-terminal end of α-melanocyte-stimulating hormone (α-MSH, positions 11 to 13), which is cut from the POMC precursor protein, and it is studied as the smallest fragment of that hormone that keeps measurable activity in laboratory models. With one lysine, one proline and one valine, it is among the simplest research peptides: a molecular weight of 342.43 g/mol and a single positive charge at neutral pH.
KPV Labs supplies KPV as a lyophilized powder in 10 mg vials. Each lot is tested by ILS Laboratories for HPLC purity, identity against a reference standard and net content, with a fentanyl screen, and the certificate is published here before the material is sold through Klow.bio.
What is KPV research material?
KPV research material is KPV supplied for laboratory research (C16H30N4O4, 342.43 g/mol) in lyophilized powder form, sold by lot. Each lot's identity, purity and net content are documented by an independent laboratory in a published certificate of analysis.
How is KPV characterized?
Three questions are answered for every lot, each by a different method:
- Is it the right compound? The laboratory runs the sample and a reference standard of the named compound under the same HPLC conditions; identity is confirmed when the main peak elutes at the reference standard’s retention time.
- How much of the sample is that compound? HPLC-UV reports the main peak's share of detected peak area. Current lots: 99.69%.
- How much peptide is in the vial? Net content is measured directly.
Endotoxin (LAL) and microbial DNA (PCR) results are added where those tests are run.
What has not been established
A certificate of analysis describes the specific sample tested on its test date. It does not establish stability afterward, sequence order beyond what mass confirmation shows, results for other lots, or suitability for any particular purpose.
KPV at a glance
- Product
- KPV
- Type
- Synthetic tripeptide, 3 residues
- Also known as
- Lys-Pro-Val, α-MSH(11-13)
- CAS number
- 67727-97-3
- Molecular formula
- C16H30N4O4
- Molecular weight
- 342.43 g/mol (average)
- Form
- Lyophilized powder
- Vial sizes
- 10 mg
- Purity, current lots
- 99.69% (HPLC-UV)
- Purity specification
- ≥95%
- Identity
- Confirmed by HPLC retention-time match on every lot
- Testing laboratory
- ILS Laboratories (independent)
- Current lot
- KB-96378, reported Oct 8, 2026
- Operated by
- Klow Labs LLC, Chicago, IL
- Where to order
- klow.bio
KPV research resources
Every KPV resource on kpv.bio, organized from chemistry to documentation.
KPV specifications
Formula, molecular weight, sequence, modifications and release specification.
QualityQuality and supply chain
Sourcing, specifications, batch documentation and release.
TestingAnalytical testing
How every lot is tested, reviewed and released.
TestingHPLC analysis of KPV
Retention time, peaks, area normalization and results by lot.
DocumentationCertificates of analysis
Every lot's full results, plus the complete testing records.
DocumentationHow to read a KPV COA
What each section means and what a COA does and doesn't establish.
DocumentationVerify a lot
Look up any KPV lot by the number on the vial.
AnalysisPurity, content and net content
Three different numbers, kept apart.
HandlingStorage and stability
Degradation pathways and lyophilized peptide handling.
ReferenceGlossary
Definitions for every term on a KPV certificate.
Research materialKPV research material
Sizes, current lots and availability. Purchasing is handled through Klow.bio.
Research references
Published sources
- NCBI Gene: POMC (proopiomelanocortin, the α-MSH precursor). National Center for Biotechnology Information, NIH. www.ncbi.nlm.nih.gov/gene/5443
- NCBI Gene: MC1R (melanocortin 1 receptor). National Center for Biotechnology Information, NIH. www.ncbi.nlm.nih.gov/gene/4157
- Wilm M. Principles of electrospray ionization. Mol Cell Proteomics. 2011. PMC3134074. pmc.ncbi.nlm.nih.gov/articles/PMC3134074
- U.S. FDA. Q2(R2) Validation of Analytical Procedures. 2024. fda.gov
- U.S. FDA. Pyrogen and Endotoxins Testing: Questions and Answers. Revised 2026. fda.gov
KPV Labs analytical documentation
- Lot KB-96378: 10 mg, 99.69% purity, reported Oct 8, 2026
- KPV testing records (all tests, all lots; CSV available)
Editorial scope
KPV Labs research content covers molecular characteristics, peptide structure, analytical chemistry, purity and identity testing, certificates of analysis, lot documentation and laboratory storage and handling.
It does not cover dosing, administration instructions, protocols, personal use or medical advice.
Latest updates
Buy KPV
10 mg vials. Current lot KB-96378 tested at 99.69% purity with identity confirmed by HPLC retention-time match against a reference standard. Current purchasing is available through Klow.bio.